MedTrace Logo

Optimizing Liver MRI Using Breath-Holding With and Without Oxygen

NCT07135401 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2026-04-13

No results posted yet for this study

Summary

The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy adults, ages 18-75.

The main questions it aims to answer are:

* Does breath-holding at end-expiration improve image quality in abdominal MRI scans?
* Does adding oxygen while breath-holding further reduce motion artifacts in abdominal MRI scans?

Researchers will compare breath-holding with and without oxygen to see if using oxygen improves image quality during MRI scans.

Participants will:

* Be pre-screened for MRI safety and trained on breath-hold procedures
* Have one non-contrast abdominal MRI scan at the University of California San Francisco (UCSF) China Basin Imaging Center
* Use two different breath-holding techniques during the scan, with and without oxygen
* Complete one study visit lasting about 45 minutes to 1 hour

Conditions

  • MRI
  • MRI Image Enhancement

Interventions

OTHER

Breath-hold conditions

Functional Residual Capacity/End-Expiration (breath-hold technique) with/without oxygen to optimize MRI image quality.

Sponsors & Collaborators

Principal Investigators

  • John P Roberts, MD · University of California, San Francisco

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2026-06-01
Completion
2026-08-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07135401 on ClinicalTrials.gov