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Chinese Migrant Population Health Cohort

NCT07124949 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 26000

Last updated 2025-08-20

No results posted yet for this study

Summary

The Chinese Migrant Population Health Cohort is a prospective, multi-center study jointly initiated by Professor Yong Ji, President of Harbin Medical University, and Academician Guoqiang Chen, President of Hainan Medical University, in collaboration with regional partners. It targets older adults (≥60 years) who engage in seasonal migration between cold (Heilongjiang) and tropical (Hainan) regions. The primary objective is to investigate cardiovascular and metabolic disease risks, underlying biological and environmental mechanisms, and effective preventive strategies in this unique population.

Participants are recruited from both origin and destination sites and undergo standardized baseline assessments, including questionnaires, physical examinations, medical imaging, biospecimen collection (blood, stool, hair, nails), and environmental exposure monitoring. Longitudinal follow-up includes periodic reassessments, remote monitoring, and data linkage with hospital information systems to capture health outcomes.

The study aims to:

Define migration-related health risk profiles and disease phenotypes.

Elucidate biological and environmental mechanisms influencing disease onset and progression.

Develop AI-driven risk prediction models and evaluate targeted interventions through nested randomized controlled trials.

Translate findings into clinical guidelines and scalable cross-regional health management models.

This is the first cohort in China to systematically investigate the health impacts of seasonal migration in older adults. By integrating epidemiology, multi-omics, environmental data, and health policy translation, the study seeks to improve continuity of care, strengthen climate adaptation, and promote healthy ageing.

Conditions

Interventions

OTHER

No intervention

no intervention

Sponsors & Collaborators

  • Hainan Medical College

    collaborator OTHER

  • Jinwei Tian

    lead OTHER

Eligibility

Min Age
60 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-23
Primary Completion
2030-04-30
Completion
2030-04-30

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07124949 on ClinicalTrials.gov