Construction and Application of Precise Diagnosis and Treatment System for Thyroid-associated Ophthalmopathy
NCT07124572 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500
Last updated 2025-08-15
Summary
This study aims to develop the deep learning-based system that integrates multimodal information to automatically diagnose, stage, and grade thyroid-associated ophthalmopathy (TAO), assist in treatment decision-making, and predict patient prognosis, thereby providing novel tools to support clinical management.
Conditions
- Thyroid Associated Ophthalmopathy
Interventions
- OTHER
-
Imaging and ocular examinations
2D and 3D Facial photography, blinking videos, orbital CT and MRI images, fundus images and images of nine gaze positions are taken. Clinical information is recorded. Quality of life is assessed. Ocular examinations, such as visual acuity, levator function, exophthalmos measurement, strabismus test, visual field examination, axial length measurement, OCT, OCTA are made.
Sponsors & Collaborators
-
Second Affiliated Hospital, School of Medicine, Zhejiang University
lead OTHER
Eligibility
- Min Age
- 7 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-10-01
- Primary Completion
- 2030-10-01
- Completion
- 2031-10-01
Countries
- China
Study Locations
More Related Trials
-
Real World Study to Describe the Effectiveness and Safety of Teprotumumab Among Thyroid Eye Disease Patients
NCT07085117 ·Status: COMPLETED
-
Artificial Intelligence-assisted Contrast-enhanced Ultrasound Diagnosis of Thyroid Nodules
NCT05982821 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Sequential Hormone Therapy and Tetuzumab Therapy in Patients With Moderate to Severe TAO in the Active Stage After Glucocorticoid Treatment.
NCT07152366 ·Status: RECRUITING ·Phase: PHASE4
-
Multiparameter Ultrasound Based-AI for the Diagnosis of Thyroid Nodules
NCT05816629 ·Status: ENROLLING_BY_INVITATION
-
Evaluation of the Efficacy and Safety Observation of IBI311 Treatment in Patients With Inactive TAO
NCT07152392 ·Status: RECRUITING ·Phase: PHASE4
-
Using A Novel Classification System in Intravenous GCs Therapy of TAO: A Multi-central, Randomized, Open, Superior Trial
NCT03107078 ·Status: UNKNOWN ·Phase: PHASE4
-
Near Infrared Fluorescent Imaging in Thyroid and Parathyroid Surgery With the Fluobeam(TM) System of Fluoptics
NCT01598727 ·Status: COMPLETED ·Phase: PHASE1
-
The Prospective Study of Standard Treatment of Graves Disease Iodine 131 and Prevention of Adverse Reactions
NCT01204359 ·Status: UNKNOWN ·Phase: PHASE3
-
Identification of Important Symptoms and Diagnostic Hypothyroidism Patients Using Machine Learning Algorithms
NCT06112886 ·Status: COMPLETED
-
Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy
NCT02203682 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Feasibility of Disease Managing Mobile App for Hyperthyroidism
NCT05828732 ·Status: UNKNOWN ·Phase: NA
-
Biosignals by Wearable Devices in Hypothyroidism
NCT04332770 ·Status: COMPLETED
-
Thyroid-Associated Ophthalmopathy Subtypes and Orbital Antibodies
NCT00430547 ·Status: COMPLETED ·Phase: NA
-
Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy
NCT07124065 ·Status: ACTIVE_NOT_RECRUITING
-
Artificial Intelligence-enable Electrocardiogram for Diagnosis and Outcome in Hyperthyroidism
NCT05675670 ·Status: UNKNOWN ·Phase: NA
-
Rituximab (RTX) Therapy in Patients With Active TAO
NCT02378298 ·Status: COMPLETED ·Phase: PHASE4
-
Early Detection of Endolymphatic Hydrops in Hypothyroid Patients
NCT05334771 ·Status: UNKNOWN
-
The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction
NCT06275373 ·Status: RECRUITING
-
Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total Thyroidectomy
NCT05022667 ·Status: COMPLETED ·Phase: NA
-
The Protection of Thyroid Function in IMRT for Nasopharyngeal Carcinoma
NCT06268600 ·Status: RECRUITING ·Phase: NA
-
Rituximab Treatment of Graves' Dysthyroid Ophthalmopathy
NCT00424151 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Initial Management in Patients With Differentiated Thyroid Cancer in the Real World in China
NCT04857086 ·Status: UNKNOWN
-
Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathy
NCT03066076 ·Status: UNKNOWN ·Phase: PHASE3
-
Evaluating an AI Tool for Detecting Thyrotoxic States
NCT07017907 ·Status: NOT_YET_RECRUITING
-
Differential Diagnosis and Clinical Treatment Strategies of Thyroid Nodules.
NCT02953288 ·Status: UNKNOWN