Laying the Foundation for Building a Resilient KPNC Community in the Face of Worsening Air Quality Due to Wildfire Smoke
NCT07118189 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-11-20
Summary
The overarching goal of this project is to conduct a pilot intervention in high-risk Kaiser Permanente Northern California patients with chronic obstructive pulmonary disease to mitigate their exposure to poor air quality and decrease exacerbations of lung disease.
Conditions
- Chronic Obstructive Pulmonary Disease (COPD)
- Exacerbation of COPD
- Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions
- DEVICE
-
N95 masks and indoor air cleaner
Participants who are randomized into the intervention will receive N95 masks to be worn outdoors and an indoor air cleaner in the room that the participant spends the most time in their home. Both intervention and control arms will receive education.
Sponsors & Collaborators
-
Kaiser Permanente
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-07
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- United States
Study Locations
More Related Trials
-
Observational Multicenter Non-interventional Study on COPD Patients Treatment Strategies at the Time of Hospital Discharge and Within 12 Months of Follow-up on an Outpatient Primary Care Basement
NCT02346292 ·Status: COMPLETED
-
Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
NCT03263130 ·Status: RECRUITING
-
Study of Microbiological Diversity in Exhaled Air in COPD and Free of COPD
NCT05437198 ·Status: RECRUITING
-
Air Pollution and Health of COPD Patients
NCT05076630 ·Status: COMPLETED
-
Genomic/ Proteomic/ Metabonomic Profiling in Chronic Obstructive Pulmonary Disease (COPD)
NCT00655694 ·Status: WITHDRAWN
-
Regeneration of Bronchial Epithelium During Chronic Obstructive Pulmonary Disease
NCT02873988 ·Status: COMPLETED
-
In This Study, the Sponsor Would Like to Collaborate with Institution and Investigator to Aggregate Participants Data and to Pilot Its Software Algorithm Using Machine Learning and Threshold Based Methods for Predicting Exacerbations and Deterioration Within a 60 Days Period Post-discharge
NCT06798688 ·Status: NOT_YET_RECRUITING
-
Biomarker Assay Validation in Healthy Smokers and COPD Smokers and Ex-smokers
NCT02490358 ·Status: COMPLETED
-
Severe Chronic Obstructive Pulmonary Disease Inhalation Profiles Comparison
NCT02076269 ·Status: COMPLETED ·Phase: PHASE1
-
Inhalation Profiling of Idiopathic Pulmonary Fibrosis (IPF) Patients
NCT02058602 ·Status: COMPLETED ·Phase: PHASE1
-
COPD Patient-Powered Research Network
NCT02803242 ·Status: RECRUITING
-
Biomarkers of iNOS Activity in COPD, Asthma, Healthy Control
NCT00159302 ·Status: WITHDRAWN
-
Influence of Electronic Cigarettes in the Evaluation of the Inflammatory Response in Patients With a Diagnosis of COPD
NCT02892396 ·Status: COMPLETED
-
Study of PneumRx Endobronchial Coil System in Treatment of Subjects With Severe Emphysema
NCT03360396 ·Status: COMPLETED ·Phase: NA
-
Molecular, Cytological Features and Genetic Susceptibility of COPD Attributable to Different Environmental Exposures
NCT02220387 ·Status: COMPLETED
-
Study to Explore the Relationship Between the Level of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device Against Existing Measures of Lung Disease
NCT04061291 ·Status: COMPLETED
-
Causes, Characteristics and Mechanisms of Infective Exacerbations in Subjects With Asthma and Chronic Obstructive Pulmonary Disease (COPD)
NCT00512954 ·Status: COMPLETED
-
Smog Induced Indoor Air Pollution in Homes of Chronic Obstructive Pulmonary Disease Patients.
NCT02775487 ·Status: WITHDRAWN
-
Occurrence of Potential Bacterial and Viral Pathogens in Stable Chronic Obstructive Pulmonary Disease and During Acute Exacerbations of the Disease, in Asia Pacific
NCT03151395 ·Status: COMPLETED ·Phase: NA
-
Smoking-induced EGF-dependent Reprogramming of Airway Basal Cell Function
NCT01974180 ·Status: TERMINATED
-
EXhaled Hydrogen Peroxide As a Marker of Lung diseasE (EXHALE) Pilot Study.
NCT03055923 ·Status: COMPLETED
-
COPD Originates in Polluted Air
NCT02236039 ·Status: COMPLETED ·Phase: NA
-
Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke
NCT02168673 ·Status: COMPLETED
-
Burden of Hospitalized Pneumonia in Korea COPD Population
NCT03046134 ·Status: UNKNOWN
-
Identification of Volatile Organic Compounds in Exhaled Air During Exacerbation of Chronic Obstructive Pulmonary Disease
NCT02529891 ·Status: TERMINATED