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Serial Assessment of Fertility Experiences

NCT07116772 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2026-02-04

No results posted yet for this study

Summary

The SAFE study is a long-term research project that watches people with sickle cell anemia (SCA) over time. The main goal is to see how a medicine called hydroxyurea affects their growth, puberty, and ability to have children. A second goal is to see how hydroxyurea affects pregnancy outcomes, by comparing people who take the medicine to those who don't.

Conditions

Sponsors & Collaborators

  • Caribbean Institute for Health Research, University of West Indies

    collaborator UNKNOWN

  • Centro de Obstetricia y Ginecologia Recruiting Santo Domingo, Dominican Republic

    collaborator UNKNOWN

  • Children's Hospital Medical Center, Cincinnati

    lead OTHER

Principal Investigators

  • Russell E Ware, MD, PhD · Children's Hospital Medical Center, Cincinnati

Eligibility

Min Age
8 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-10
Primary Completion
2035-05-19
Completion
2035-12-31

Countries

  • Dominican Republic
  • Jamaica
  • Tanzania

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07116772 on ClinicalTrials.gov