The Role of POLE Mutation in High Risk Endometrial Cancer.
NCT07114653 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2025-08-11
Summary
The actual role of POLE mutations in high-risk endometrial cancer is undetermined. The main question it aims to answer is:
What is the prevalence of POLE mutations in high-risk endometrial cancer case? What is the impact of POLE mutations in real world high-risk endometrial cancer case?
Conditions
- Endometrial Neoplasms
Sponsors & Collaborators
-
Far Eastern Memorial Hospital
lead OTHER
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-01
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Taiwan
Study Locations
More Related Trials
-
Ketohexokinase Isoforms in Endometrial Cancer.
NCT03931265 ·Status: UNKNOWN
-
Expression of Altered Glycosyltransferases, Mucins, and RTKs in Human Ovarian and Endometrial Cancers
NCT02638402 ·Status: UNKNOWN
-
Analysis of miRNA Expression in Endometrial Cancer
NCT04845425 ·Status: UNKNOWN
-
The Development of Human Immunologic Assays Specific to Folate Receptor Antigen
NCT00155935 ·Status: UNKNOWN ·Phase: NA
-
Translational Study of MSS, TP53 Mutation and Chromosome Instability Relationship in Endometrial Carcinoma
NCT06521684 ·Status: NOT_YET_RECRUITING
-
Early Detection of Endometrial Cancer Using Plasma Cell-free DNA Fragmentomics
NCT06083779 ·Status: UNKNOWN
-
Genetic Studies in Liver Cancer Patients
NCT00172640 ·Status: UNKNOWN
-
The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2)
NCT05624827 ·Status: UNKNOWN ·Phase: NA
-
Cell-free DNA Methylation for Epithelial Ovarian Cancer
NCT04651946 ·Status: UNKNOWN ·Phase: PHASE2
-
Research on the Heterogeneity of Taiwanese Breast Cancer Patients by Next Generation Sequencing (NGS) Tools
NCT04626440 ·Status: RECRUITING
-
Molecular and ctDNA Characterization of High-Risk Endometrial Cancer
NCT07062016 ·Status: RECRUITING
-
Early Detection of Ovarian Cancer Using Plasma Cell-free DNA Fragmentomics (Retrospective Study)
NCT05693974 ·Status: UNKNOWN
-
Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer
NCT00364715 ·Status: COMPLETED
-
The Final Diagnosis and Treatment Result of Metastatic Cervical Carcinoma of Unknown Primary
NCT00302588 ·Status: UNKNOWN
-
Validation of DNA Methylation Biomarkers for Oral Cancer Detection
NCT01945697 ·Status: COMPLETED
-
Characterizing the Cross-sectional Approach to Investigate the Prevalence of Tissue BRCA1/2 Mutations in Newly Diagnosed Advanced Ovarian Cancer Patients
NCT04222465 ·Status: COMPLETED
-
The Impact of Epigenetic MMRd in Endometrial carcinomas-a Real World Study
NCT05334303 ·Status: UNKNOWN
-
Reliability and Interest of Circulating Tumor DNA in Endometrial Cancers.
NCT04456972 ·Status: COMPLETED ·Phase: NA
-
The Registry of Genetic Alterations of Taiwan Biliary Tract Cancer
NCT05036486 ·Status: ACTIVE_NOT_RECRUITING
-
A Multiomics Study Based on the Dynamic Evolution of Endometrial Carcinogenesis
NCT06007300 ·Status: NOT_YET_RECRUITING
-
Prospective Multi-omics Observational Study of Gynecological Rare Pathological Tumors
NCT05985941 ·Status: NOT_YET_RECRUITING
-
The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma
NCT00302562 ·Status: UNKNOWN
-
A Qualitative Exploration of the Impact of Positive BRCA1/2 Mutation Status on the Lives of Young Women
NCT00858078 ·Status: COMPLETED
-
Role of Senescence in the Development of Endometrial Cancer
NCT03338985 ·Status: UNKNOWN ·Phase: NA
-
Characterization of Ovarian Cancer Stem Cell
NCT01367353 ·Status: UNKNOWN ·Phase: NA