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Pressure-Volume Loop Assessment in Valvular Heart Disease

NCT07112391 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2025-09-16

No results posted yet for this study

Summary

The VHD PV loop study intends to assess invasive right ventricular to pulmonary artery (RV-PA) coupling in patients with valvular heart disease (VHD). Invasive RV-PA coupling is measured by using conductance catheters, the gold standard assessment for ventricular physiology. Several non-invasive parameters have been reported as surrogates for this complex physiological entity, but none of them has been tested against the gold-standard in this population. Based on this, our main objective is to assess the correlation of imaging derived RV-PA coupling in comparison to the invasive measurement.

Conditions

  • Heart Failure
  • Structural Heart Disease
  • Interventional Cardiology

Interventions

OTHER

Observational Invasive Hemodynamic Assessment

Collection and analysis of invasive hemodynamic data obtained through routine cardiac catheterization performed as part of standard care. No intervention is mandated by the study protocol.

Sponsors & Collaborators

  • Fédération Française de Cardiologie

    collaborator OTHER

  • Nantes University Hospital

    lead OTHER

Principal Investigators

  • Robin LE RUZ, MD, PhD · Hospital of Nantes

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-04
Primary Completion
2027-09-04
Completion
2027-09-04

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07112391 on ClinicalTrials.gov