Generation of Cell Banks and Biomarker Isolation From Patients With Amyotrophic Lateral Sclerosis (ALS) (HCD-SLA)

Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)

NCT03268603 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2

Autologous Cultured Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in ALS Patients.

NCT01051882 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Intramuscular Infusion of Autologous Bone Marrow Stem Cells in Patients With Amyotrophic Lateral Sclerosis

NCT02286011 ·Status: UNKNOWN ·Phase: PHASE1

Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve Biopsy

NCT07268833 ·Status: RECRUITING

Identification of Diagnostic And Prognostic Biomarkers From Amyotrophic Lateral Sclerosis (ALS) Skin and Adipose Samples

NCT01948102 ·Status: COMPLETED

Creation of a Bank of Fibroblast From Patients With Amyotrophic Lateral Sclerosis: Pilot Study

NCT01639391 ·Status: COMPLETED ·Phase: NA

Safety/Efficacy Study for the Treatment of Amyotrophic Lateral Sclerosis

NCT01082653 ·Status: SUSPENDED ·Phase: PHASE1

Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project

NCT06820008 ·Status: RECRUITING

TRIAL READY (Clinical Trial Readiness)

NCT03912987 ·Status: ACTIVE_NOT_RECRUITING

The Safety, Tolerability and Preliminary Efficacy of Derived Motor Neuron Progenitor Cells (XS228CN) in Subjects With Amyotrophic Lateral Sclerosis

NCT07118319 ·Status: RECRUITING ·Phase: PHASE1

Collection of Blood Samples for DNA in Motor Neuron Disease

NCT00362362 ·Status: COMPLETED

Muscular Biomarkers in Amyotrophic Lateral Sclerosis

NCT02670226 ·Status: COMPLETED ·Phase: NA

CNS10-NPC-GDNF Delivered to the Motor Cortex for ALS

NCT05306457 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1

Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis (ALS)

NCT01142856 ·Status: COMPLETED ·Phase: PHASE1

CNS10-NPC-GDNF for the Treatment of ALS

NCT02943850 ·Status: COMPLETED ·Phase: PHASE1

A Dose-escalation Safety Trial for Intrathecal Autologous Mesenchymal Stem Cell Therapy in Amyotrophic Lateral Sclerosis

NCT01609283 ·Status: COMPLETED ·Phase: PHASE1

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

NCT06100276 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2

Comprehensive Biomarker Profiling of the IFN-α Pathway in Amyotrophic Lateral Sclerosis Patient Biofluids

NCT07260981 ·Status: COMPLETED

Neuroinflammation in Amyotrophic Lateral Sclerosis - Mechanisms and Therapeutic Perspectives: a Translational Pilot Study Among ALS Patients

NCT02424669 ·Status: UNKNOWN ·Phase: NA

Autologous Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT01777646 ·Status: COMPLETED ·Phase: PHASE2

A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS

NCT06917924 ·Status: RECRUITING

A Longitudinal Analysis of Biomarkers in Patients With ALS

NCT05309408 ·Status: UNKNOWN

Analysis of Human ALS Tissues and Registry of ALS Patients

NCT05067179 ·Status: RECRUITING

Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

NCT05116943 ·Status: RECRUITING

The Myelin Disorders Biorepository Project

NCT03047369 ·Status: RECRUITING