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Lifestyle Habits and Metabolic Dysfunction-Associated Steatotic Liver Disease in Youth

NCT07095010 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 224

Last updated 2025-08-01

No results posted yet for this study

Summary

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the most common cause of chronic liver disease in children and adolescents. Lifestyle factors are modifiable risk factors that may play a key role in both the prevention and management of the disease. However, existing data on the association between lifestyle and MASLD in pediatric populations are limited and often focus on isolated aspects such as diet or physical activity, with little attention given to other parameters like sleep habits. The aim of the present study is to comprehensively investigate the association between lifestyle factors, including dietary habits, physical activity, sedentary activities, and sleep habits, and the presence of MASLD in a sample of 224 children and adolescents with overweight or obesity. The study will include newly diagnosed MASLD patients compared to matched controls without the disease. A wide range of assessments will be conducted, including anthropometric measurements, body composition analysis, liver elastography, biochemical testing, and standardized lifestyle questionnaires. This study seeks to fill important research gaps and explore potential associations between lifestyle habits and pathophysiological markers involved in the onset and progression of MASLD.

Conditions

  • Metabolic Dysfunction-Associated Steatotic Liver Disease
  • Childhood Obesity

Sponsors & Collaborators

  • Children 's Hospital, Agia Sophia

    collaborator UNKNOWN

  • Harokopio University

    lead OTHER

Principal Investigators

  • Meropi D Kontogianni · Harokopio University Athens, Kallithea, Greece

Eligibility

Min Age
10 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-01-10
Primary Completion
2024-10-31
Completion
2024-12-20

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07095010 on ClinicalTrials.gov