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Colon-delivered Riboflavin and Gut Microbiota Composition

NCT07093463 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-03-19

No results posted yet for this study

Summary

Recent studies suggest B-vitamins such as riboflavin to possess prebiotic-like effects. However, there is still a lack of understanding of the exact host health benefits vs. conventional systemically available vitamin forms. The present study explores the benefit of colon-delivered vitamin B2 vs. conventional vitamin B2 in comparison to placebo in an aging population on gut microbiota and metabolic activity as well as gut health.

Conditions

  • Microbiome Dysbiosis
  • Gut Health

Interventions

DIETARY_SUPPLEMENT

Colon-delivered riboflavin

10 mg of colon-delivered riboflavin

DIETARY_SUPPLEMENT

Conventional riboflavin

10 mg of conventional riboflavin

OTHER

Microcrystalline Cellulose

10 mg microcrystalline cellulose

Sponsors & Collaborators

  • Analyze & Realize

    collaborator NETWORK

  • dsm-firmenich Switzerland AG

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-18
Primary Completion
2026-08-31
Completion
2026-09-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07093463 on ClinicalTrials.gov