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Understanding Freezing of Gait Using Brain Signals and Virtual Reality

NCT07092995 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2026-02-17

No results posted yet for this study

Summary

Freezing of gait - the inability to start or continue walking - is a particularly disabling problem in Parkinson's disease that has few treatment options. This project records human brain activity from deep brain stimulation (DBS) devices during walking and freezing of gait episodes to understand the pathophysiology of freezing of gait. Findings will lay the foundation for the development of new treatment strategies that address this disabling symptom.

Conditions

  • Parkinson&Amp;#39;s Disease
  • Freezing of Gait
  • Freezing of Gait Symptoms in Parkinson&Amp;#39;s Disease

Interventions

BEHAVIORAL

VR Freezing Task

Walking overground in immersive virtual reality (VR) environments that provoke freezing episodes

BEHAVIORAL

Dual Task

Walking overground with and without concomitant performance of secondary cognitive or motor task

BEHAVIORAL

External Cueing

Walking overground in immersive virtual reality (VR) environments that provoke freezing episodes with and without addition of visual and auditory cues.

Sponsors & Collaborators

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-11-01
Primary Completion
2030-03-31
Completion
2030-03-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07092995 on ClinicalTrials.gov