Evaluation of Tretinoin Cream on the Integrity of Aged Forearm Skin
NCT07084116 · Status: ENROLLING_BY_INVITATION · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2025-07-24
Summary
The purpose of this research is to determine whether once nightly application of tretinoin 0.1% cream to forearm skin reduces the frequency of skin tears and bruising (solar purpura), and changes skin thickness over a period of 6 months.
Conditions
- Skin Tear
- Solar Purpura
- Dermatoporosis
Interventions
- DRUG
-
Tretinoin 0.1% cream
Tretinoin 0.1% cream formulation.
- DRUG
-
Bland cream (non-drug)
Bland cream formulation.
Sponsors & Collaborators
- lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-07-14
- Primary Completion
- 2026-01-01
- Completion
- 2026-02-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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