A Study in Healthy Men to Test How Bosentan Influences the Amount of Nerandomilast in the Blood
NCT07081932 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2025-10-14
Summary
The main objective of this trial is to investigate the effect of bosentan, a moderate Cytochrome P450 (CYP) 3A inducer on the single dose pharmacokinetics of nerandomilast.
Conditions
- Healthy
Interventions
- DRUG
-
Nerandomilast
Nerandomilast
- DRUG
-
Bosentan
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-08-26
- Primary Completion
- 2025-09-27
- Completion
- 2025-10-08
Countries
- Germany
Study Locations
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