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Comparing Two Different Norepinephrine Infusion Rates for Prophylaxis Against Spinal-induced Hypotension in Elderly

NCT07077265 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 84

Last updated 2026-03-24

No results posted yet for this study

Summary

The current study aims to determine whether norepinephrine infusion rate (0.07 mcg/kg/min) is non-inferior to the higher dose (0.1 mcg/kg/min) in maintaining intraoperative blood pressure maintaining blood pressure of elderly patients during hip surgery

Conditions

  • Spinal Aneshtesia
  • Hypotension After Spinal Anesthesia
  • Elderly (People Aged 65 or More)

Interventions

DRUG

Norepinephrine (0.1 μg/kg/min)

The patients will receive norepinephrine infusion at a rate 1 mL/kg/hour of 6 mcg/mL solution.

DRUG

Norepinephrine (0.07 μg/kg/min)

The patients will receive NE infusion at a rate 1 mL/kg/hour of 4.2 mcg/mL solution.

Sponsors & Collaborators

  • Kasr El Aini Hospital

    lead OTHER

Principal Investigators

  • Maha Mostafa, MD · Cairo University Kasr Alainy Faculty of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-01
Primary Completion
2025-12-30
Completion
2025-12-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07077265 on ClinicalTrials.gov