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Topical Icariin on Acne and Acne Scars

NCT07076784 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2026-03-05

No results posted yet for this study

Summary

The goal of this clinical trial is to examine whether topical application of icariin can improve acne and atrophic acne scars in adults. The main questions it aims to answer are:

* Does icariin reduce the number of facial acne lesions and acne scars?
* What histological changes occur in acne or scar tissue after using icariin? Researchers will compare icariin to a vehicle control (3% ethanol solution) to assess its relative efficacy.

Participants will:

* Apply icariin or control solution to each side of the face twice daily for 2 months
* Visit the clinic every 4 weeks for checkup
* Receive skin biopsies before and after the study period, if they consent to this procedure

Conditions

Interventions

DRUG

Icariin

Topical application of 3% icariin solution

DRUG

Vehicle Control

Topical application of 3% ethanol solution

Sponsors & Collaborators

  • Seoul National University Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
39 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-21
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • South Korea

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07076784 on ClinicalTrials.gov