A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults
NCT07066722 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 126
Last updated 2026-03-09
Summary
The aim of the study is to gather information on how the drug behaves in healthy adults, how it is absorbed, and how it interacts when taken with other medicines.
Conditions
- HIV Infections
Interventions
- DRUG
-
VH4524184
VH4524184 will be administered.
- DRUG
-
Itraconazole
Itraconazole will be administered.
- DRUG
-
Rifabutin
Rifabutin will be administered.
- DRUG
-
Phenytoin
Extended phenytoin sodium will be administered.
- DRUG
-
Metformin will be administered.
- DRUG
-
Digoxin
Digoxin will be administered.
Sponsors & Collaborators
-
ViiV Healthcare
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-07-07
- Primary Completion
- 2025-12-17
- Completion
- 2025-12-17
- FDA Drug
- Yes
Countries
- United States
Study Locations
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