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A Study of the Intestinal Microbiota in Children and Adolescents With Eating Disorders. A Perspective From Psychoneuroimmunology

NCT07066033 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 158

Last updated 2025-07-15

No results posted yet for this study

Summary

The goal of this observational study is to learn if behavioral and psychological factors are associated with the intestinal microbiota composition and function in children and adolescents with eating disorders (ED). The main questions it aims to answer are:

* Are there any differences between the microbiota composition and function in adolescent patients with eating disorders and healthy adolescents?
* Are the dietary pattern and other lifestyle habits associated with the intestinal microbiota composition in patients with a recent onset eating disorder?
* Is it possible to predict the treatment response at one year by looking at any of the psychological and biological factors measured in the patients at baseline?
* Are there any differences in the intestinal microbiota among patients with different subtypes of anorexia nervosa (restrictive, binge-purging, atypical) or with avoidance/restrictive food intake disorder (ARFID)? Researchers will compare the results with those obtained from a group of healthy children and adolescents matched by sex and age to find out if the associations observed differ between ED and control participants.

Participants with ED will fill in different lifestyle questionnaires and psychological tests; they will also undergo anthropometrical measurements and will provide fecal and blood samples at baseline and one year later. Healthy participants will provide the same lifestyle information, anthopometrical measurements and stool and blood samples. They will only undergo the baseline evaluation.

Conditions

  • Eating Disorders in Adolescence
  • Eating Disorders in Children

Sponsors & Collaborators

  • Spanish National Research Council (ICTAN, CSIC)

    collaborator UNKNOWN

  • FUNDACION PARA LA INVESTIGACIÓN BIOMÉDICA HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESUS

    collaborator UNKNOWN

  • Esther Nova

    lead OTHER_GOV

Principal Investigators

  • Esther Nova, PhD · Spanish National Research Council (CSIC - ICTAN)

  • Mar Faya, PhD, MD · Hospital Infantil Universitario Niño Jesús

Eligibility

Min Age
7 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-29
Primary Completion
2026-12-31
Completion
2027-08-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07066033 on ClinicalTrials.gov