The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity
NCT07052539 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2025-07-04
Summary
This research study wants to learn about Chronic Kidney Disease (CKD) with Obesity, and Heart Failure with preserved Ejection Fraction (HFpEF) and better ways to evaluate these diseases. HFpEF means that the heart is not able to fill properly with blood while it is resting so the amount of blood pumped out to the body is less than it would be if it was filling properly. The study is being done to describe the differences in how the kidneys handle protein and salt in participants with HFpEF and obesity compared to healthy persons.
Conditions
- Chronic Kidney Disease
- Heart Failure With Preserved Ejection Fraction (HFPEF)
- Obesity (Disorder)
Interventions
- OTHER
-
High protein and sodium meal
Meal with 1g/kg protein content and 3900mg sodium
Sponsors & Collaborators
-
University of Mississippi Medical Center
lead OTHER
Principal Investigators
-
Marissa C Tio, MD · University of Mississippi Medical Center
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-07-22
- Primary Completion
- 2026-06-30
- Completion
- 2026-07-31
Countries
- United States
Study Locations
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