Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer
NCT07046936 · Status: SUSPENDED · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2026-05-18
Summary
The purpose of this research study is to see if patients with endometrial and ovarian cancer are willing to complete physical and cognitive assessments before treatment and again after treatment has ended.
Conditions
- Gynecologycal Cancer
Interventions
- DIAGNOSTIC_TEST
-
muscle sample
For participants undergoing standard of care interval cytoreductive surgery via laparotomy, a skeletal muscle biopsy from the rectus abdominis muscle (1 cm x 1 cm x 1 cm, \~300 mg) will be collected. For participants who undergo standard of care interval cytoreductive surgery with a laparoscopic approach, a skeletal muscle biopsy will be taken from either the rectus abdominis (1 cm x 1 cm x 1 cm, \~300 mg) or the psoas (1 cm x 0.5 cm x 0.5 cm, \~200 mg) muscle.
- OTHER
-
blood draw
A total of approximately 60mL or 4 tablespoons of blood will be collected throughout the study
Sponsors & Collaborators
-
Wake Forest University Health Sciences
lead OTHER
Principal Investigators
-
Bumsoo Ahn, PhD · Wake Forest University Health Sciences
Eligibility
- Min Age
- 50 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-10
- Primary Completion
- 2027-04-30
- Completion
- 2027-04-30
Countries
- United States
Study Locations
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