MedTrace Logo

Microbiome Modulation by PEMF on Plaque Induced Mucositis in Human Jaws

NCT07045636 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 35

Last updated 2026-05-01

No results posted yet for this study

Summary

To evaluate the impact of Pulsed Electromagnetic Field (PEMF) on mucositis induced in humans around dental implants and correlate these possible effects with the proteomic profile of implants with and without PEMF and teeth. The hypothesis is that PEMF may modulate bacterial biofilm formation around dental implants and enhance the host response following plaque-induced peri-implant mucositis. Secondary analysis will be the increase in the soft tissue volume using Intra-oral scanning (IOS).

Conditions

  • Microbial Colonization
  • Peri-Implantitis

Interventions

OTHER

PEMF abd Sham (control)

Dental implants receive MED that could (test) or could not (control/SHAM) be activated to emit PEMF

DIAGNOSTIC_TEST

Teeth wih gingivits

Comparison with dental implants

Sponsors & Collaborators

  • Harvard School of Dental Medicine

    collaborator OTHER

  • Hospital Israelita Albert Einstein

    collaborator OTHER

  • Jamil awad shibli

    lead OTHER

Principal Investigators

  • Jamil A Shibli, PhD · Guarulhos University

  • Cinthya Massari, DDS · Guarulhos University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-11
Primary Completion
2025-05-11
Completion
2025-05-11

Countries

  • Brazil

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07045636 on ClinicalTrials.gov