Study of SHR-A2102 Combined Other Antitumor Drugs in Advanced Breast Cancer
NCT07041437 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2025-06-27
Summary
Our study is aimed to evaluate the efficacy and safety of SHR-A2102 combined other antitumor treatments in advanced breast cancer.
Conditions
Interventions
- DRUG
-
SHR-A2102
ADC
- DRUG
-
Adebrelimab
PD-L1 inhibitor
Sponsors & Collaborators
-
Fudan University
lead OTHER
Principal Investigators
-
Hongxia Wang, Chief physician · Fudan University
-
Xichun Hu, Chief physician · Fudan University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-06-30
- Primary Completion
- 2026-09-30
- Completion
- 2027-01-31
Countries
- China
Study Locations
More Related Trials
-
A Study of SHR-A1811 and Fulvestrant, With or Without HS-10352, in Locally Advanced or Metastatic Breast Cancer Patients
NCT06788197 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast Cancer
NCT07317778 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
SHR-1811 Combined With Carboplatin in the Treatment of Advanced Breast Cancer With HER2 Expression
NCT07047443 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast Cancer
NCT06149130 ·Status: RECRUITING ·Phase: PHASE2
-
SHR-A1811 Combine With Pyrotinib for Locally Advanced/Metastatic HER2 Positive Breast Cancer
NCT07132242 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Adebrelimab Combined With Fluzoparib in HRD-positive HR +/HER2- Advanced Breast Cancer
NCT06254066 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of Trastuzumab Rezetecan Followed by CDK4/6 Inhibitors and Endocrine Therapy in HR+/HER2-Low/Ultra-Low Advanced Breast Cancer
NCT07037199 ·Status: RECRUITING ·Phase: PHASE2
-
Study of ADCs Combined With Adebrelimab in HER2-negative Advanced Breast Cancer
NCT06433609 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Evaluate the Efficacy and Safety of Adebrelimab Combined With Chemotherapy With or Without Radiotherapy as Neoadjuvant Treatment for HER2-Negative Locally Advanced Breast Cancer
NCT06908668 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
SHR-A1921 Combined With Bevacizumab in Triple-negative Breast Cancer With Brain Metastases
NCT06210438 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
SHR-A1811 Plus Pertuzumab as Neoadjuvant Therapy for Early or Locally Advanced HR-Positive HER2-Positive Breast Cancer: A Prospective, Open-Label, Phase II Study
NCT07307287 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Trial of SHR-1210 (an Anti-PD-1 Antibody) in Combination With Apatinib in Patients With Advanced TNBC
NCT03394287 ·Status: COMPLETED ·Phase: PHASE2
-
SHR-A1811 for HER2-positive Breast Cancer With Suboptimal Neoadjuvant Response
NCT07129187 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib and Fluzoparib in Patients With TNBC
NCT03945604 ·Status: COMPLETED ·Phase: PHASE1
-
Molecularly Targeted Umbrella Study in Luminal Advanced Breast Cancer
NCT04355858 ·Status: UNKNOWN ·Phase: PHASE2
-
Precision Treatment of HR+ HER2- Advanced Breast Cancer Based on SNF Molecular Subtyping
NCT06561022 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in HR Positive/HER2 Low Breast Cancer
NCT06340230 ·Status: RECRUITING ·Phase: PHASE2
-
Abemaciclib, Palbociclib or Dalpiciclib Combined with Endocrine Therapy As First-line Treatment in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer
NCT06344780 ·Status: ACTIVE_NOT_RECRUITING
-
A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC
NCT07002177 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Efficacy of Everolimus Combined With First-line Endocrine Therapy for HR+/HER2- SNF1-subtype Advanced Breast Cancer
NCT05949541 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase Ⅰb/Ⅱ Clinical Study of SHR-A1811 Combined With Other Therapies in Patients With HER2 Low Advanced or Metastatic Breast Cancer.
NCT05792410 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial
NCT05814354 ·Status: RECRUITING ·Phase: PHASE3
-
SHR-A1811 Plus Pertuzumab in the Neoadjuvant Treatment of HER2 Positive BC
NCT06927180 ·Status: RECRUITING ·Phase: PHASE2
-
Reverse Triple Negative Immune Resistant Breast Cancer
NCT05076682 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of SHR-A1811 Monotherapy or Combined With Pyrotinib Maleate as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients
NCT05635487 ·Status: RECRUITING ·Phase: PHASE2