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Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser

NCT07036302 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-05-19

No results posted yet for this study

Summary

More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized. This study will evaluate the effects of chemical peels with 35% TCA (trichloroacetic acid) and two types of fractional laser in orofacial harmonization procedures. A sample of 100-120 participants at least 18 years of age, male or female, with complaints of melasma (n=36 to 40), acne scars (n=36 to 40) or facial wrinkles (n=36 to 40) will be recruited to underwent 3 consecutive treatment sections every 30 days. Besides clinical improvements, global satisfaction scale of the professional and the patient will be measured in addition to the impact of the treatment on the quality of life of the participants and the sensory experience in relation to pain. Pre- and pos-peeling home care will be provided to measure whether they influence results or not. The aim of this study is to identify the most appropriate treatment strategy for frequent complaints in clinical practice, and among them, the one that promotes the best experience, with the shortest recovery time and is cost-effective.

Conditions

  • Melasma
  • Acne Scars - Mixed Atrophic and Hypertrophic
  • Resurfacing
  • Rejuvenation

Interventions

PROCEDURE

35% TCA combined with croton oil peel

3 sections every 30 days of 35% TCA combined with croton oil peel

PROCEDURE

Isolate 35% TCA peel

3 sections every 30 days of isolate 35% TCA peel

RADIATION

Erbium-YAG laser

3 sections every 30 days of Er-YAG laser

RADIATION

Neodymium -YAG laser Q-switched

3 sections every 30 days of ND-YAG laser

Sponsors & Collaborators

  • Cavalca & Cortelli private research center

    collaborator UNKNOWN

  • Jose Roberto Cortelli

    lead OTHER

Principal Investigators

  • Sheila C Cortelli, Doctorate · University of Taubate

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-02
Primary Completion
2025-12-02
Completion
2026-12-31

Countries

  • Brazil

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07036302 on ClinicalTrials.gov