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University-Based Chagas Testing in Salta Province, Argentina

NCT07033325 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 5000

Last updated 2025-06-24

No results posted yet for this study

Summary

The goal of this observational study is to improve access to diagnosis and treatment for chronic Trypanosoma cruzi infection among university students of all ages and genders at the National University of Salta (UNSa), Argentina. The main questions it aims to answer are:

* What is the seroprevalence and geographic distribution of T. cruzi infection in UNSa students?
* Can voluntary point-of-care tests performed at university serve as an effective opportunity for timely diagnosis and linkage to care for Chagas disease?

Participants will:

1. Be offered a RDTs (WL Check Chagas, Wiener Lab) during their regular activities in the university.
2. If RDT is positive, be referred to the health system for confirmatory testing and treatment.
3. Receive follow-up support by trained staff via phone. A subgroup of RDT-negative students will have serum samples preserved and analyzed later via ELISA to verify RDT accuracy.

Conditions

  • Chagas Disease
  • Trypanosoma Cruzi Infection
  • Chronic Chagas Disease

Interventions

DIAGNOSTIC_TEST

Rapid diagnostic test (RDT) for Trypanosoma cruzi infection.

Rapid diagnostic tests (RDTs) for the detection of Trypanosoma cruzi infection are performed in university facilities, outside of a clinical care setting, using a point-of-care approach. The study population includes adult male and female participants from the university community. This intervention differs from most existing strategies that target exclusively women of reproductive age and/or newborns to control vertical transmission; instead, it focuses on broader population-based screening and linkage to care for chronic infections.

Sponsors & Collaborators

  • Universidad Nacional de Salta

    collaborator OTHER

  • Mundo Sano Foundation

    lead OTHER

Principal Investigators

  • Adriana Echazu, PhD · Mundo Sano Foundation

  • Ruben O Cimino, PhD · Instituto de Investigaciones de Enfermedades Tropicales, Univeridad Nacional de Salta

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-11
Primary Completion
2025-08-01
Completion
2026-02-01

Countries

  • Argentina

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07033325 on ClinicalTrials.gov