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Burden of Schistosomiasis and Soil-transmitted Helminth Infections in Schoolchildren in Banfora, Burkina Faso

NCT06973200 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2025-05-15

No results posted yet for this study

Summary

A cross-sectional study will be conducted among 300 schoolchildren in the Banfora region, including 120 in urban and 180 in rural areas, to assess the prevalence of schistosomiasis and soil-transmitted helminth infections. All children with S. mansoni and/or S. haematobium infections at enrolment will then be treated with dihydroartemisinin-piperaquine (DP) and followed up on days 1, 2, 3, 4, 28, and 42 to assess the efficacy and safety of DP. At the end of the study, all children (infected and uninfected) will receive praziquantel and albendazole according to national recommendations.

Conditions

  • Schistosomiasis in Children
  • Soil Transmitted Helminth (STH) Infections
  • Malaria Infection
  • Anaemia
  • Malnutrition in Children

Interventions

COMBINATION_PRODUCT

Dihydroartemisin-piperaquine

All children with S. mansoni and/or S. haematobium infections at enrolment will then be treated with dihydroartemisinin-piperaquine (DP) and followed up on days 1, 2, 3, 4, 28, and 42 to assess the efficacy and safety of DP.

Sponsors & Collaborators

  • Institut de Recherche en Sciences de la Sante, Burkina Faso

    collaborator OTHER_GOV

  • University of Ghana

    collaborator OTHER

  • Centre MURAZ/Institut National de Santé Publique

    lead OTHER_GOV

Principal Investigators

  • Mamoudou Cissé, MD, MSc, PhD · Centre MURAZ/Université Nazi BONI

Eligibility

Min Age
5 Years
Max Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-11-11
Primary Completion
2024-12-21
Completion
2025-02-25

Countries

  • Burkina Faso

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06973200 on ClinicalTrials.gov