A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma
NCT07030699 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2026-04-07
Summary
The researchers are doing this study to find out whether the combination of epcoritamab with tafasitamab and lenalidomide is a safe and effective treatment for relapsed or refractory DLBCL. This is the first time the combination of drugs is being tested.
Conditions
Interventions
- DRUG
-
Epcoritamab
Subcutaneous, once weekly in cycles 1-3; every 4 weeks cycles 4-12
- DRUG
-
Oral, daily on days 1-21 of a 28-day cycle
- DRUG
-
Tafasitamab
Intravenous, once weekly during cycles 1-3, then every 2 weeks during cycle 4-12
Sponsors & Collaborators
-
Genmab
collaborator INDUSTRY - collaborator INDUSTRY
-
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Pallawi Torka, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-08-13
- Primary Completion
- 2026-03-31
- Completion
- 2026-03-31
- FDA Drug
- Yes
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