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Association of Genetic Variants With Myopia

NCT07030153 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2025-06-22

No results posted yet for this study

Summary

This study aims to identify genetic factors linked to myopia, including those that influence a person's risk of developing it and how quickly it progresses (like changes in eye length). It will also examine how different treatments-such as low-dose atropine drops, orthokeratology lenses, specialized glasses, and increased outdoor time-interact with these genes. Finally, the research will develop a genetic risk score to help tailor personalized myopia prevention and treatment plans.

Conditions

  • Myopia

Interventions

GENETIC

Oral swab DNA analyzed for myopia-related gene variants

Beyond detecting links between gene variants and myopia development, the testing analyzes how these variants influence treatment effectiveness. The aim is to enable early risk prediction and personalized treatment guidance for children through oral DNA testing.

Sponsors & Collaborators

  • Beijing New Vision Eye Hospital

    collaborator UNKNOWN

  • High Myopia Control Alliance (HIMALAYA)

    collaborator UNKNOWN

  • Beijing Visionly Plus Eye Hospital

    lead OTHER

Eligibility

Min Age
6 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-01
Primary Completion
2028-08-31
Completion
2028-12-31

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07030153 on ClinicalTrials.gov