Improving Medication Management in World Trade Center Responders
NCT07022990 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2025-06-15
Summary
By 2030, the majority of World Trade Center (WTC) rescue and recovery workers (responders) will be aged 65 and over and at risk for aging-related conditions and consequences including the concurrent use of five or more medications (i.e., polypharmacy). The purpose of this research study is to investigate an educational approach targeting polypharmacy through de-prescribing unnecessary and burdensome medications via the support of informed discussions between WTC responders and their prescribing physicians.
Conditions
- Polypharmacy
Interventions
- OTHER
-
Educational brochure for deprescribing
Study participant will be provided information (i.e., educational brochure) about one of the five medication classes participants may be taking that are known to have potential side effects for older adults: proton pump inhibitors (PPIs), benzodiazepine (BZs) and non-benzodiazepine sedative hypnotics ("Z-drugs"), first-generation antihistamines (FGA), and skeletal muscle relaxants (SMR) to determine their necessity.
Sponsors & Collaborators
-
Icahn School of Medicine at Mount Sinai
lead OTHER
Principal Investigators
-
Fred Ko, MD · Icahn School of Medicine at Mount Sinai
Study Design
- Allocation
- NA
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-04-08
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
More Related Trials
-
Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents
NCT03655405 ·Status: COMPLETED ·Phase: NA
-
Older Adults' Readiness to Stop Prescribed Medications
NCT05996237 ·Status: COMPLETED
-
Team Approach to Polypharmacy Evaluation and Reduction
NCT02562352 ·Status: COMPLETED ·Phase: NA
-
Engaging Patients to Promote Deprescribing
NCT04294901 ·Status: COMPLETED ·Phase: NA
-
Optimising Medication With Focus on Deprescribing in Frail Older People With Multidose Drug Dispensing Systems
NCT05609981 ·Status: COMPLETED ·Phase: NA
-
Deprescribing in a Long Term Care Facility
NCT03091153 ·Status: COMPLETED ·Phase: NA
-
Reducing Costs by Deprescribing Medications
NCT04553107 ·Status: COMPLETED ·Phase: NA
-
A Trial to De-prescribe Inappropriate Medications in the Community Dwelling Elderly
NCT02053194 ·Status: COMPLETED ·Phase: PHASE4
-
DBI - Tool for Medication Reviews in Older People
NCT02317666 ·Status: COMPLETED ·Phase: NA
-
Bundled Hyperpolypharmacy Deprescribing
NCT05616689 ·Status: COMPLETED ·Phase: NA
-
Improving Posthospital Medication Management of Older Adults Through Health IT
NCT00611091 ·Status: COMPLETED ·Phase: NA
-
Prescribing Outcomes of a GP-Targeted Deprescribing Educational Intervention: A Cluster Randomized Trial
NCT06470308 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
MODIFY or Medication Review in Primary Care Study
NCT05705284 ·Status: RECRUITING ·Phase: NA
-
Psychological and Clinical Factors That Predict Intent to Deprescribe Medications Among Older Adults
NCT04676282 ·Status: COMPLETED
-
Population Health Approach to Optimizing Medications in Older Adults
NCT06110156 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Reducing CNS-Active Medications to Prevent Falls and Injuries in Older Adults
NCT05689554 ·Status: COMPLETED ·Phase: NA
-
Assessment and Management of Multiple Drug Use in Elderly Chronic Disease Patients
NCT07180368 ·Status: RECRUITING
-
Medication Use and Quality of Life Among Older People
NCT05123313 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Polypharmacy Outpatient Clinic
NCT03911934 ·Status: COMPLETED ·Phase: NA
-
Pharmaceutical Care and Clinical Outcomes for the Elderly Taking Potentially Inappropriate Medication
NCT00844025 ·Status: UNKNOWN ·Phase: NA
-
Polypharmacy Among Internal Medicine Patients
NCT05756400 ·Status: ACTIVE_NOT_RECRUITING
-
Improving Safety By Computerizing Outpatient Prescribing
NCT00235027 ·Status: COMPLETED ·Phase: NA
-
Pharmacist-led Medicines Management Outpatient Service
NCT01534559 ·Status: COMPLETED ·Phase: PHASE4
-
Team Approach to Polypharmacy Evaluation and Reduction
NCT02942927 ·Status: COMPLETED ·Phase: NA
-
Medication Empowerment and Deprescription for Safety (MEDS) Study
NCT04612166 ·Status: COMPLETED ·Phase: NA