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Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital

NCT07022236 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1

Last updated 2025-06-15

No results posted yet for this study

Summary

Thyroid dysfunction is a prevalent endocrine disorder that significantly impacts the health of patients with chronic kidney disease (CKD), particularly those undergoing dialysis. The prevalence of thyroid dysfunction in dialysis patients has been reported to range from 20% to 60%, highlighting the need for routine screening and management in this vulnerable group (Kuo et al., 2024). Thyroid hormones play a crucial role in regulating various physiological processes, and their dysregulation can lead to complications such as cardiovascular disease, anemia, and impaired quality of life, which are particularly concerning in the dialysis population (Smith et al., 2024).

The relationship between CKD and thyroid dysfunction is complex and multifactorial. Uremic toxins can interfere with the hypothalamic-pituitary-thyroid axis, leading to alterations in thyroid hormone production and metabolism. Recent studies have shown that inflammation and oxidative stress associated with CKD can further exacerbate thyroid dysfunction (Johnson et al., 2024). Understanding these mechanisms is essential for developing effective management strategies for thyroid health in dialysis patients.

Conditions

  • Dialysis; Complications

Interventions

DIAGNOSTIC_TEST

Thyroid profile

Thyroid dysfunction in patients undergoing hemogdialysis in sohag university hospital

Sponsors & Collaborators

  • Sohag University

    lead OTHER

Eligibility

Min Age
13 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-04-13
Primary Completion
2025-10-13
Completion
2025-10-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07022236 on ClinicalTrials.gov