Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia Longitudinal Assessment Study
NCT07018401 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 62
Last updated 2025-09-23
Summary
This is a multicenter U.S. longitudinal study evaluating patients with hereditary hemorrhagic telangiectasia who participated in the PATH-HHT clinical trial of pomalidomide for the treatment of HHT. This study is a longitudinal assessment of safety and effectiveness of pomalidomide in HHT in clinical trial participants following completion of the double-blind, placebo-controlled study.
Conditions
- Hereditary Hemorrhagic Telangiectasia (HHT)
Interventions
- DRUG
-
Oral pomalidomide up to 4 mg daily
Sponsors & Collaborators
-
The Cleveland Clinic
collaborator OTHER -
University of North Carolina, Chapel Hill
collaborator OTHER -
University of California, San Francisco
collaborator OTHER - collaborator OTHER
- collaborator OTHER
-
University of California, San Diego
collaborator OTHER -
University of Florida
collaborator OTHER -
Medical College of Wisconsin
collaborator OTHER - collaborator OTHER
- collaborator OTHER
-
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Ellen Zhang, MD · Stanford University
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-05-01
- Primary Completion
- 2025-04-08
- Completion
- 2026-06-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
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