Efficacy of Leuconostoc Mesenteroides
NCT07017088 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2025-06-12
Summary
Excessive alcohol intake can cause dehydration, digestive issues, oxidative stress, and hangover symptoms like headache and fatigue. Toxic metabolites like acetaldehyde and ROS contribute to liver damage. Chronic drinking activates harmful pathways like MEOS and increases inflammation. Gut-liver axis disruption also worsens hangovers. Probiotics, such as Leuconostoc mesenteroides, may help restore gut health and reduce toxicity, but more clinical research is needed.
Conditions
- Alcohol Drinking
- Alcohol Drinking Related Problems
Interventions
- DIETARY_SUPPLEMENT
-
Leuconostoc mesenteroides
Control vs Experiment
Sponsors & Collaborators
-
Wonju Severance Christian Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-08-13
- Primary Completion
- 2024-09-13
- Completion
- 2025-02-28
Countries
- South Korea
Study Locations
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