Conversion Surgery After Target Therapy or Immunotherapy in Stage IV Gastric Cancer
NCT07009600 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 124
Last updated 2025-06-06
Summary
In this retrospective study, investigators conducted a comprehensive investigation of the factors influencing postoperative prognosis in patients with stage IV gastric cancer undergoing conversion surgery. Specifically, investigators examined the impact of targeted therapy or immune check point inhibitors (ICIs) in combination with preoperative chemotherapy on (1) prognostic differences based on initial progression (invading adjacent organs) and metastatic site (peritoneum, distant lymph node \[LN\]) at the time of stage IV gastric cancer diagnosis and (2) conversion surgery outcomes and pathological complete response (pCR).
Conditions
- Gastric Cancer Stage IV
Interventions
- DRUG
-
immune check point inhibitors (PD-1 inhibitors), target therapy (trastuzumab)
Sponsors & Collaborators
-
Samsung Medical Center
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-01-01
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
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