Hair Isotope Analysis for Early Cancer Detection
NCT07006909 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2025-06-05
Summary
Cancer is a major health challenge, and early detection is crucial for improving patient outcomes. Research has shown that cancer can alter the way the body processes nutrients. This study aims to explore whether these metabolic changes can be detected through a simple, non-invasive method: analysing hair. Hair grows slowly over time, potentially capturing subtle metabolic changes that occur during cancer development. By studying the nitrogen stable isotope composition in hair samples donated by individuals diagnosed with cancer, we aim to identify potential early markers of the disease. Participants will be asked to donate a small strand of hair, which will be analysed using a laboratory technique called Isotope Ratio Mass Spectrometry (IRMS). The findings from this study could contribute to new, non-invasive screening tools for early cancer detection.
Conditions
Sponsors & Collaborators
-
University of Reading
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-01
- Primary Completion
- 2030-05-30
- Completion
- 2030-05-30
Countries
- United Kingdom
Study Locations
More Related Trials
-
Characterization & Comparison of Drugable Mutations in Primary and Metastatic Tumors, CTCs and cfDNA in MBCpatients
NCT02626039 ·Status: COMPLETED
-
Analysis of Whole Body Magnetic Resonance Imaging and Liquid Biopsy for Early Detection of Cancer in Patients With a Strong Family History of Cancer
NCT05868486 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Diagnosis of Multiple Cancer and Monitoring of Minimal Residual Tumors After Treatment Using Blood and High-Sensitivity Genetic Analysis Techniques
NCT07035587 ·Status: RECRUITING
-
Rare Tumors and Cancer Predisposition in Individuals and Families
NCT05350761 ·Status: RECRUITING
-
Study of Circulating Cancer Cells in Patients With Metastatic Breast, Ovarian, Colon, or Pancreatic Cancer
NCT00898781 ·Status: TERMINATED
-
Study of Healthy Cohort for Early Detection of Cancer
NCT05193305 ·Status: RECRUITING
-
Omics of Cancer: OncoGenomics
NCT05431439 ·Status: WITHDRAWN
-
Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer
NCT03892096 ·Status: COMPLETED
-
HER-2 Mutations in Tumor Samples From Patients With Advanced Non-Small Cell Lung Cancer Treated on Clinical Trial ECOG-2598
NCT00896909 ·Status: COMPLETED
-
Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers
NCT00568490 ·Status: RECRUITING
-
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer
NCT00001163 ·Status: ACTIVE_NOT_RECRUITING
-
Detecting Cancers Earlier Through Elective Plasma-based CancerSEEK Testing
NCT04213326 ·Status: COMPLETED
-
Tumor Antigen Discovery for Innovative Cancer Immunotherapies in HCC: from Benchside to Bedside (HepAnt)
NCT06905262 ·Status: RECRUITING
-
Clearance of NNAL and Cotinine From Second-hand Smoke in Hair and Urine
NCT00863824 ·Status: WITHDRAWN
-
Laboratory Study Using Samples From Patients With Non-Small Cell Lung Cancer Treated on Clinical Trial CASE-2507
NCT00907699 ·Status: WITHDRAWN
-
Discovery and Validation of Plasma DNA Methylation Biomarker for Detection of Stomach Cancer
NCT03076567 ·Status: COMPLETED
-
Recurrence Monitoring in NSCLC Using Circulating Tumor DNA
NCT03878537 ·Status: UNKNOWN
-
Early Detection of Ovarian Cancer Using Plasma Cell-free DNA Fragmentomics (Prospective Study)
NCT05693987 ·Status: UNKNOWN
-
Intraoperative Detection of Residual BCC by Fast Raman
NCT03482622 ·Status: UNKNOWN
-
Biomarkers in Stored Tumor Samples From Younger Patients With Liver Cancer
NCT00899002 ·Status: WITHDRAWN
-
Detecting Abnormal Blood Clotting in Patients With Metastatic Cancer Undergoing Surgery
NCT00096590 ·Status: COMPLETED
-
Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized Kidney Cancer
NCT00908739 ·Status: WITHDRAWN
-
DNA Repair and Genetic Susceptibility to Lung Cancer
NCT00611598 ·Status: COMPLETED
-
Prediction of Residual Disease by Circulating DNA Detection After Potentiated Radiotherapy for Locally Advanced Head and Neck Cancer
NCT05710679 ·Status: RECRUITING ·Phase: NA
-
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
NCT00132704 ·Status: COMPLETED