Comparison of the Hemodynamic Effects of Ketamine - Dexmedetomidine (Ketodex) Versus Propofol-ketamine Admixture (Ketofol) During Induction of Anesthesia in Elderly: A Randomized Comparative Study
NCT07002073 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 102
Last updated 2026-04-21
Summary
To compare the hemodynamic effects of Ketamine-Dexmedetomidine admixture (Ketodex) versus propofol-ketamine admixture (Ketofol) during induction of anesthesia in elderly
Conditions
- Ketamine-dexmedetomidine Induction of Anesthesia
Interventions
- DRUG
-
Intravenous Induction of Anesthesia
To compare incidence of hypotension following ketodex versus ketofol during intavenous induction of general anesthesia in elderly patients
Sponsors & Collaborators
-
Kasr El Aini Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-04-01
- Primary Completion
- 2025-11-30
- Completion
- 2026-02-15
Countries
- Egypt
More Related Trials
-
Dexmedetomidine Versus Ketamine-midazolam Sedation in Awake Fiberoptic Intubation in Suspected Difficult Airway
NCT06946212 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine Versus Ketamine Versus Midazolam in Endoscopic Procedures
NCT04597268 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Adding Low Dose Ketamine or Fentanyl to Propofol-dexmedetomidine as Total Intravenous Anesthesia
NCT06031883 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dexmedetomidine Versus Dexmedetomidine with Ketamine in Mechanically Ventilated ARDS Patients
NCT05951387 ·Status: COMPLETED ·Phase: PHASE4
-
The Use of Ketamine and Dexmedetomidine in Intensive Care Sedation
NCT04096768 ·Status: UNKNOWN ·Phase: PHASE3
-
Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section
NCT07022821 ·Status: RECRUITING ·Phase: PHASE4
-
Ketamine Versus Fentanyl for Induction of Anesthesia in Septic Shock
NCT03251170 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures
NCT07190612 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries
NCT07108764 ·Status: RECRUITING ·Phase: NA
-
Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial
NCT07214701 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Dexmedetomidine Versus Dexmedetomidine and Ketamine (Ketodex) in Ear and Nose Surgeries
NCT06981494 ·Status: RECRUITING ·Phase: NA
-
Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.
NCT06327399 ·Status: RECRUITING ·Phase: PHASE2
-
Comparison Between the Effect of Dexmedetomidine _midazolam and ketamine_midazolam Combination
NCT07074262 ·Status: COMPLETED ·Phase: NA
-
Effect of Dexmedetomidine and Propofol on Regional Cerebral Tissue Oxygen Saturation
NCT03817112 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine in IVRA
NCT05123170 ·Status: COMPLETED ·Phase: PHASE4
-
Comparative Study Between Dexmedetomidine & Neostigmine as an Adjuvant to Local Anesthetic Mixture in Peribulbar Block in Vitreoretinal Surgeries
NCT06501352 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting
NCT06368219 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries
NCT04018157 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Prevention of Shivering Associated With Spinal Anesthesia
NCT06082076 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Dexmedetomidine, Ketamine and Dexmetedomidine-Ketamine Combination for Control of Shivering During Regional Anaethesia
NCT03302351 ·Status: COMPLETED ·Phase: PHASE4
-
Is it Possible to Replace Fentanyl in Anesthesia for Minor Procedures?
NCT03806374 ·Status: COMPLETED ·Phase: NA
-
Comparison of Ketamine and Etomidate During Rapid Sequence Intubation in Trauma Patients
NCT04120870 ·Status: TERMINATED ·Phase: NA
-
Comparsion of IV Dexmedetomidine, Tramdol and Ketamine for Post Spinal Anesthesia Shivering.
NCT05311722 ·Status: UNKNOWN ·Phase: PHASE3
-
Efficacy of Intravenous Dexketoprofen and Tenoxicam on Propofol Associated Injection Pain
NCT02285972 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Topical Airway Block on Hemodynamic Stability Post Induction of Anaesthesia in Cardiac Surgeries
NCT06395727 ·Status: COMPLETED ·Phase: PHASE4