Dobutamine During Major Abdominal Surgery
NCT07000994 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2026-04-29
Summary
The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.
Conditions
- Intraoperative Myocardial Depression
Interventions
- DRUG
-
Dobutamine
In patient assigned to dobutamine administration, dobutamine (concentration: 5 mg mL-1) will be administered with an infusion rate of 3 µg kg-1 min-1 (ideal body weight).
- OTHER
-
Routine care
In patients assigned to routine care, intraoperative hemodynamic management will be in accordance with routine care.
Sponsors & Collaborators
-
University of Hamburg-Eppendorf
lead OTHER
Principal Investigators
-
Alina Bergholz, MD · University Medical Centre Hamburg-Eppendorf
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-06-16
- Primary Completion
- 2026-01-28
- Completion
- 2026-02-27
Countries
- Germany
Study Locations
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