Dobutamine During Major Abdominal Surgery

NCT07000994 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-04-29

No results posted yet for this study

Summary

The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.

Conditions

  • Intraoperative Myocardial Depression

Interventions

DRUG

Dobutamine

In patient assigned to dobutamine administration, dobutamine (concentration: 5 mg mL-1) will be administered with an infusion rate of 3 µg kg-1 min-1 (ideal body weight).

OTHER

Routine care

In patients assigned to routine care, intraoperative hemodynamic management will be in accordance with routine care.

Sponsors & Collaborators

  • University of Hamburg-Eppendorf

    lead OTHER

Principal Investigators

  • Alina Bergholz, MD · University Medical Centre Hamburg-Eppendorf

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-16
Primary Completion
2026-01-28
Completion
2026-02-27

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07000994 on ClinicalTrials.gov