MedTrace Logo

Arterial Pressure Based Cardiac Output for Goal-Directed Therapy in Abdominal Surgery

NCT00549419 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2009-12-23

No results posted yet for this study

Summary

The purpose of this study is to determine whether the early identification and more precise intervention of goal-directed intraoperative plasma volume expansion and catecholamine therapy using arterial pressure based cardiac output (APCO) measurement in addition to normal vital signs will improve postoperative organ function, in particular renal function, in patients undergoing major abdominal surgery.

Conditions

  • Major Abdominal Surgery

Interventions

DRUG

Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine

The Control group will be assessed using the standard care of traditional vital signs

DRUG

Goal-directed hemodynamic therapy

Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine

DRUG

Standard of care

Ringers lactate, hydroxyethyl starch; norepinephrine, dobutamine

Sponsors & Collaborators

  • Klinikum Ludwigshafen

    lead OTHER

Principal Investigators

  • Stefan W. Suttner, M.D. Ph.D. · Klinikum Ludwigshafen

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-10-31
Primary Completion
2009-01-31
Completion
2009-04-30

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00549419 on ClinicalTrials.gov