Revisiting the Concept of Nerve Sparing Radical Hysterectomy
NCT06999824 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 15
Last updated 2025-05-31
Summary
Nerve-sparing radical hysterectomy aims to preserve the autonomic innervation of pelvic organs. In most studies, the preservation of the parasympathetic component of pelvic innervation is achieved by sparing the lymphovascular-neural tissue located at the base of the lateral paracervical tissue. This study explores an alternative surgical technique based on a different anatomical pathway of parasympathetic fibers, running more cranially and deeply within the pararectal space.
Conditions
Sponsors & Collaborators
-
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
lead OTHER
Principal Investigators
-
Grazia Casadei · Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
-
Valentina Chiappa · Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-06-01
- Primary Completion
- 2026-03-01
- Completion
- 2027-05-01
Countries
- Italy
Study Locations
More Related Trials
-
Role of Bladder Training During Post-operative Hospital Stay After Radical Hysterectomy in Patients
NCT01907646 ·Status: COMPLETED ·Phase: PHASE2
-
Minimally Invasive Simple Hysterectomy in Low Risk Cervical Cancer
NCT06416748 ·Status: RECRUITING ·Phase: NA
-
Radical Versus Simple Hysterectomy and Pelvic Node Dissection With Low-risk Early Stage Cervical Cancer
NCT01658930 ·Status: COMPLETED ·Phase: NA
-
Study of Laparoscopic Radical Hysterectomy Based on Space Anatomy in Patients With IB3 and IIA2 Cervical Cancer
NCT06759480 ·Status: NOT_YET_RECRUITING
-
Removal of Urinary Catheter After Radical Surgery
NCT03570593 ·Status: COMPLETED ·Phase: NA
-
Minimally Invasive Surgery Versus Open Radical Hysterectomy in Presumably Early Stage Cervical Cancer: a Retrospective Multicenter Non-inferiority Study Comparing Overall and Progression-free Survival.
NCT07120529 ·Status: RECRUITING
-
A Multicentre Trial of Nerve-Spring Radical Hysterectomy vs. Radical Hysterectomy for Cervical Cancer
NCT01886508 ·Status: UNKNOWN ·Phase: NA
-
2D Versus 3D Radical Laparoscopic Hysterectomy for Cervical Cancer: a Prospective Randomized Trial
NCT02320578 ·Status: COMPLETED ·Phase: NA
-
A Research on Hidden Blood Loss in Open Radical Hysterectomy and Pelvic Lymphadenectomy
NCT03628118 ·Status: UNKNOWN
-
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
NCT06802198 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Laparoscopic or Abdominal Radical Hysterectomy for Cervical Cancer(Stage IA1 With LVSI, IA2)
NCT04934982 ·Status: RECRUITING ·Phase: NA
-
Transcutaneous Electrical Nerve Stimulation in Nerve-Sparing Radical Hysterectomy: Effects on Bladder Management and Quality of Life in Cervical Cancer
NCT07070687 ·Status: COMPLETED ·Phase: NA
-
Feasibility of a Trial of Laparoscopic Hysterectomy Versus Laparoscopic Sub-Total Hysterectomy
NCT01825915 ·Status: UNKNOWN ·Phase: NA
-
A Research on Hidden Blood Loss in Laparoendoscopic Single-site Radical Hysterectomy With Pelvic Lymphadenectomy
NCT03626493 ·Status: UNKNOWN
-
Laparoscopic Supracervical Hysterectomy and Sacropexy Versus Hysteropexy Study
NCT02345954 ·Status: UNKNOWN ·Phase: NA
-
Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSIL
NCT06325592 ·Status: COMPLETED
-
2D Versus 3D Radical Laparoscopic Hysterectomy for Endometrial Cancer: a Prospective Randomized Trial
NCT02320565 ·Status: COMPLETED ·Phase: NA
-
LESs Surgical Radicality for EaRly Stage Cervical Cancer
NCT02613286 ·Status: COMPLETED ·Phase: NA
-
Pelvic Drains After Radical Hysterectomy in Treating Patients With Uterine, Cervical, or Vaginal Cancer
NCT00003267 ·Status: COMPLETED ·Phase: PHASE3
-
Long-term Outcomes After Laparoscopic Subtotal and Total Hysterectomy
NCT05421156 ·Status: NOT_YET_RECRUITING
-
Impact of a Minimally Invasive Approach to Laparoscopic Hysterectomy on Postoperative Recovery
NCT05102032 ·Status: UNKNOWN ·Phase: NA
-
Comparative Effectiveness of Uterine Repair Surgery on Preventing Recurrence of Cesarean Sar Pregnancy
NCT06485180 ·Status: COMPLETED ·Phase: NA
-
Closure of the Uterine Artery at Its Origin vs at the Cervix: a Randomized Trial
NCT04156932 ·Status: COMPLETED ·Phase: NA
-
Role of Hysterectomy in the Treatment of Borderline Ovarian Tumors
NCT06825468 ·Status: COMPLETED
-
Perioperative Outcomes of Common Methods of Minimally Invasive Contained Tissue Extraction
NCT02496130 ·Status: COMPLETED