Glucokinase Activator in Monogenic Diabetes
NCT06976658 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 44
Last updated 2026-04-30
Summary
Evaluating a novel, allosteric glucokinase activator in monogenic diabetes secondary to inactivating glucokinase mutations: a randomised, cross-over trial
Conditions
- Diabetes Mellitus
- Monogenic Diabetes
Interventions
- DRUG
-
Dorzagliatin
Dorzagliatin 50mg bd
- DRUG
-
matched placebo
matched placebo
Sponsors & Collaborators
-
Chinese University of Hong Kong
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 74 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-04-30
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Hong Kong
Study Locations
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