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Multiprofen-CC to Reduce Pain in Hand Arthritis

NCT06966206 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2026-05-04

No results posted yet for this study

Summary

This clinical trial aims to find out if using 1 gram of Multiprofen-CC cream on the hands three times a day for 4 weeks can help reduce pain in adults with hand osteoarthritis, compared to a placebo (a cream with no active medicine). The research team will also look at how Multiprofen-CC affects hand function, opioid use, and how patients feel about their overall improvement. In addition, the research team will keep track of any side effects.

Participants will:

* Use both Multiprofen-CC and a placebo (a cream with no active medicine) during the study, in a random order.
* Be asked to apply 1 gram of cream to their hands three times a day for 2 weeks, following the manufacturer's instructions.
* Attend a visit before starting the study, after 2 weeks, and after 6 weeks.
* Report any symptoms they experience during the study.

Conditions

  • Hand Osteoarthritis

Interventions

DRUG

Multiprofen-CC™ plus standard treatment

Standard care pain medications and topical Multiprofen-CC™ (1g TID) for 2 weeks

OTHER

Placebo plus standard treatment

Standard care pain medications and visually identical topical placebo (1g TID) for 2 weeks

Sponsors & Collaborators

  • St. Joseph's Healthcare Hamilton

    lead OTHER

Principal Investigators

  • Carolyn Levis, MD, MSc, FRCS(C) · McMaster University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-09
Primary Completion
2026-12-31
Completion
2027-08-01

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06966206 on ClinicalTrials.gov