Expanded Access To Neoantigen Synthetic Long Peptide Vaccines in Patients With Local Or Metastatic Solid Tumors
NCT06963697 · Status: AVAILABLE · Type: EXPANDED_ACCESS
Last updated 2026-01-15
Summary
This is an intermediate patient expanded access protocol for treatment of patients with local or metastatic solid tumors with a neoantigen synthetic long peptide vaccine.
Conditions
Interventions
- BIOLOGICAL
-
Personalized Synthetic Long Peptide Vaccine
Neoantigen synthetic long peptide vaccines are composed of synthetic long peptides which are 8-35 amino acids in length and designed to induce immune responses to cancer neoantigens identified by exome sequencing. Neoantigen synthetic long peptide vaccines will be co-administered with poly-ICLC, an innate immune adjuvant capable of activating TLR3 and other pathways.
Sponsors & Collaborators
-
Jaime Leandro Foundation for Therapeutic Cancer Vaccines
lead OTHER
Eligibility
- Min Age
- 12 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
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