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Restricted Versus Liberal Fluid Intake for Prevention of Bronchopulmonary Dysplasia

NCT06954142 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 750

Last updated 2026-05-08

No results posted yet for this study

Summary

The aim of this study is to determine whether restricted fluid intake (135 ±5 mL/kg/day) compared to liberal fluid intake (165 ±5 mL/kg/day) from day 8 of life reduces the incidence of bronchopulmonary dysplasia (BPD) at 36 weeks postmenstrual age or prior death in preterm infants born \<30 weeks gestational age.

Conditions

  • Bronchopulmonary Dysplasia

Interventions

OTHER

Fluid restriction

Fluid restriction strategy (fluid target 135 ±5 mL/kg/d)

OTHER

Liberal fluid intake

Liberal fluid intake strategy (fluid target 165 ± 5 mL/kg/d)

Sponsors & Collaborators

  • Swiss Neonatal Network

    collaborator NETWORK

  • SwissPedNet - Swiss Research Network of Clinical Pediatric Hubs

    collaborator UNKNOWN

  • University Children's Hospital Basel

    lead OTHER

Principal Investigators

  • Sven Schulzke, Prof.MD · University Children's Hospital Basel

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
8 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-12
Primary Completion
2029-12-31
Completion
2029-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06954142 on ClinicalTrials.gov