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Profiling Vulnerability and Resilience for Mental Illness Following Viral Infections

NCT06945627 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 408551

Last updated 2025-05-14

No results posted yet for this study

Summary

This observational study aims to identify the underlying neurobiological and environmental mechanisms that influence vulnerability or resilience to mental illness in the context of infection and their contribution to severe infective outcomes in people with pre-existing mental illness. The main questions it aims to answer are:

* How do viral infections influence the development of mental illness?
* What neurobiological and environmental factors contribute to influence the development of mental illness following infection?
* How do these factors relate to the severity of infectious illness in people with pre-existing mental disorders?

Researchers will move from large population databases to well-defined, deeply characterised samples to explore the association between infection and subsequent mental health outcomes, and the biological mechanisms behind these changes.

Participants's data has already been collected.

Conditions

Interventions

OTHER

This research doesn't involve any kind of intervention on the study participants

This research doesn't involve any kind of intervention on the study participants

Sponsors & Collaborators

  • Sara Poletti

    lead OTHER

Principal Investigators

  • Sara Poletti, PhD · IRCCS Ospedale San Raffaele

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-02
Primary Completion
2026-05-31
Completion
2027-03-31

Countries

  • Belgium
  • Israel
  • Italy
  • Norway

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06945627 on ClinicalTrials.gov