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Growth Evaluation, Health Promotion, and Clinical Management in Children and Adolescents With Thalassemia

NCT06931912 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 369

Last updated 2026-02-11

No results posted yet for this study

Summary

There are nearly 300,000 patients with severe or intermediate thalassemia in China. Growth retardation is the most significant health issue for children and adolescents with transfusion-dependent thalassemia (TDT), placing a substantial economic burden on their families and a serious social strain on the labor force. Investigating the growth and development of these children and adolescents, and establishing targeted intervention plans, holds significant social value for public health practice.

1. To screen and identify pediatric patients with growth problems by conducting growth and development assessments in high-incidence areas of China, including physical development, endocrine function, nutritional status, brain function and lifestyle behaviors.
2. Implement the MENBS clinical interventions for pediatric patients with growth problems, concentrating on the following areas:

* Monitor: Continuously monitor health-related indicators through regular follow-up.
* Education: Provide health education to improve the cognition of patients and their families.
* Nutrition: Assess patients' nutritional risks and develop personalized diet plans.
* Behavior: Recommend appropriate exercise plans to promote physical development.
* Support: Conduct home visits, offer free clinics and establish a support network.
3. Repeat growth assessment for pediatric patients with growth problems after 1-year clinical interventions.
4. Evaluate the effectiveness of MENBS interventions by comparing changes in growth and development indicators.

Conditions

  • Thalassemia Intermedia
  • Thalassemia Major
  • Growth Delay
  • Puberty, Delayed

Interventions

BEHAVIORAL

MENBS clinical interventions

* Monitor: Continuously monitor health-related indicators through regular follow-up. * Education: Provide health education to improve cognition of patients and their families. * Nutrition: Assess patients' nutritional risks and develop personalized diet plans. * Behavior: Recommend appropriate exercise plans to promote physical development. * Support: Conduct home visits, offer free clinics and establish a support network.

Sponsors & Collaborators

  • Institute of Hematology & Blood Diseases Hospital, China

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2026-10-31
Completion
2026-11-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06931912 on ClinicalTrials.gov