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Human Genes and Microbiota in Early Life

NCT06926166 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20000

Last updated 2025-04-13

No results posted yet for this study

Summary

The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life and their interaction with the host on maternal-offspring health consequences in later life in the born in Guangzhou cohort study in China. Identification of the effect of microbiota in early life, as well as environmental factors and microbe-host interaction, will lead to a better understanding of disease pathogenesis and provide a foundation for targeted mechanistic investigation into the consequences of microbial-host crosstalk for long-term health. It also can result in new strategies to predict and prevent diseases in later life.

Conditions

  • Host and Microbiome
  • Pregnancy Outcomes
  • Pregnancy Complications
  • Neurodevelopmental Disorders
  • Immune Development
  • Childhood Obesity
  • Type 2 Diabetes

Interventions

OTHER

No intervention

No intervention

Sponsors & Collaborators

  • Guangzhou Women and Children's Medical Center

    lead OTHER

Principal Investigators

  • Xiu Qiu, PhD · Study Principal Investigator Guangzhou Women and Children's Medical Center, China

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-04-01
Primary Completion
2038-12-31
Completion
2038-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06926166 on ClinicalTrials.gov