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STI Testing to Enhance PrEP Use in Pregnancy

NCT06919614 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 600

Last updated 2025-07-29

No results posted yet for this study

Summary

The investigators are conducting a study in Botswana to see if offering STI testing along with expanded HIV prevention options (PrEP) helps more pregnant women start and continue using PrEP during and after pregnancy. Pregnant women (n=600) seeking antenatal care in Botswana will be enrolled and randomly assigned to receive the standard of care (standard STI assessment with no STI testing) versus STI testing for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis during pregnancy and postpartum. The investigators' hypothesis is that providing STI testing alongside PrEP offer will encourage more women to start and continue using PrEP.

Conditions

  • PrEP Adherence
  • Sexually Transmitted Infections (STIs)
  • Pregnancy

Interventions

DIAGNOSTIC_TEST

Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis testing

Xpert® CT/NG and TV testing

Sponsors & Collaborators

  • University of Washington

    collaborator OTHER

  • University of Botswana

    collaborator OTHER

  • Botswana Harvard AIDS Institute Partnership

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-18
Primary Completion
2027-08-31
Completion
2029-08-31

Countries

  • Botswana

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06919614 on ClinicalTrials.gov