The Epidemiology of Patients Treated With ATZ+BEV in Real Life Setting
NCT06903663 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2025-04-17
Summary
Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer and the third most frequent cause of cancer-related death globally.
This retrospective, multicentric study will be coordinated by Dr. Adrian Radu Vidra (Lead Investigator) from Regional Institute of Gastroenterology and Hepatology "Prof. Dr. Octavian Fodor" Cluj-Napoca (Coordinating Site) to further investigate the clinical and demographic profile of patients receiving first-line treatment with atezolizumab and bevacizumab in the real-world setting of clinical practice from Romania.
Participants already taking the combination therapy as part of their regular medical care for HCC will be followed during 3 years.
Conditions
- Hepatocellular Carcinoma (HCC)
Sponsors & Collaborators
-
MDX Research
collaborator NETWORK -
Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor
lead OTHER
Principal Investigators
-
Adrian Radu Vidra · Regional Institute of Gastroenterology and Hepatology "Prof. Dr. Octavian Fodor" Cluj-Napoca
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-04-30
- Primary Completion
- 2025-07-31
- Completion
- 2025-12-31
Countries
- Romania
Study Locations
More Related Trials
-
Atezolizumab-bevacizumab and Other Immunotherapies: Real-life Experience for Treatment of Hepatocellular Carcinoma
NCT06806579 ·Status: RECRUITING
-
Atezolizumab and Bevacizumab Combination Recommended in a Multidisciplinary Consultation Meeting in Caen for Hepatocellular Carcinoma (ABCHCaen)
NCT06416683 ·Status: COMPLETED
-
Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma
NCT05516628 ·Status: RECRUITING ·Phase: PHASE2
-
Organ-specific Responses to Atezolizumab Plus Bevacizumab in Advanced HCC
NCT04862949 ·Status: COMPLETED
-
A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular Carcinoma
NCT06006286 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Atezolizumab and Bevacizumab With Combined Radiotherapy for Advanced Hepatocellular Carcinoma
NCT05908916 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis
NCT06096779 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer
NCT05211323 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Hepatic Arterial Infusion Chemotherapy in Combination With Atezolizumab and Bevacizumab for Second-line Treatment of Patients With Recurrent Liver Cancer After Liver Transplantation
NCT05833126 ·Status: RECRUITING ·Phase: PHASE2
-
Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab
NCT05173298 ·Status: RECRUITING
-
Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer
NCT04721132 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma
NCT06323382 ·Status: RECRUITING
-
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
NCT04770896 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma
NCT04829383 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
NCT05775159 ·Status: RECRUITING ·Phase: PHASE2
-
Antiangiogenic Treatment of Hepatocellular Cancer With Bevacizumab and RAD001
NCT00775073 ·Status: COMPLETED ·Phase: PHASE2
-
An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery
NCT06117891 ·Status: ACTIVE_NOT_RECRUITING
-
Atezolizumab+Bevacizumab+SBRT in Unresectable HCC
NCT05096715 ·Status: RECRUITING ·Phase: PHASE1
-
Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Hilar Cholangiocarcinoma. A Prospective Multicenter Study.
NCT04378023 ·Status: RECRUITING
-
A Study of Avastin (Bevacizumab) and Transarterial Chemoembolisation (TACE) Treatment in Patients With Liver Cancer
NCT00576199 ·Status: COMPLETED ·Phase: PHASE2
-
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
NCT06921785 ·Status: RECRUITING ·Phase: PHASE3
-
Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Systemic Therapy
NCT05197504 ·Status: COMPLETED
-
Study to Evaluate the Efficacy and Safety of Atezolizumab and Bevacizumab as Neoadjuvant Plus Adjuvant Treatment in HCC
NCT07018947 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Transarterial Chemoembolisation Plus Bevacizumab for Treatment of Hepatocellular Carcinoma
NCT00280007 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista
NCT04487067 ·Status: COMPLETED ·Phase: PHASE3