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Comparison of the Effects of Protocols Applied After Surgical Extraction of Impacted Mandibular Third Molars

NCT06900907 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2025-03-28

No results posted yet for this study

Summary

Following the surgical extraction of the most commonly impacted mandibular third molars, the first group was planned to receive methylprednisolone, the second group hyaluronic acid, the third group ozone therapy, the fourth group laser application, and the fifth group only the routine treatment protocol. The study comparatively evaluated the effectiveness of these five groups in preventing complications such as pain, edema, and trismus that may develop after impacted third molar surgery.

Conditions

  • Tooth Impaction | {Tooth} | Dental
  • Corticosteroid
  • Hyaluronic Acid
  • Ozone
  • Laser Therapy

Interventions

DEVICE

Diode laser

A single session was applied to three points of the tooth extraction site.

COMBINATION_PRODUCT

Hyaluronic acid

1 cc of hyaluronic acid gel was placed into the extraction socket, followed by suturing.

COMBINATION_PRODUCT

Ozone

Topical ozone was applied to the extraction socket, followed by suturing.

DRUG

Methylprednisolone

In addition to the standard prescribed medication, 4 mg of oral methylprednisolone was prescribed postoperatively.

PROCEDURE

Control

Only the standard prescribed medication was provided.

Sponsors & Collaborators

  • Batman University

    lead OTHER

Principal Investigators

  • Nedim GÜNEŞ, Ass.Prof. · Dicle University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-01
Primary Completion
2017-08-30
Completion
2017-09-22

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06900907 on ClinicalTrials.gov