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Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema

NCT05466604 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2022-07-20

No results posted yet for this study

Summary

The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection. For this purpose, 60 participants with symmetrical mandibular wisdom teeth enrolled the present study. All measurements and evaluations were performed before and 1, 2, 3, and 7 days later the operation.

Conditions

  • Edema
  • Pain
  • Trismus
  • Infection, Surgical Site

Interventions

DRUG

Hyaluronidase Injection mesomedica

injection of 150 IU hyaluronidase to perioperative region, submucosally.

DRUG

Dexamethasone dekort

injection of 8 mg dexamethasone to perioperative region, submucosally.

Sponsors & Collaborators

  • Hacettepe University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-12-01
Primary Completion
2022-06-30
Completion
2022-06-30

Countries

  • Cyprus
  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05466604 on ClinicalTrials.gov