Real World Efficiency of Abrocitinib Treatment at Patients With Moderate to Severe Atopic Dermatitis Who Had Inadequate Response to Previous Biologic Therapies.
NCT06899204 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2026-04-22
Summary
This is a prospective, multi-center observational study characterizing clinical and patient reported outcomes of patients receiving abrocitinib for moderate-to-severe atopic dermatitis (M2S AD) who had inadequate response (or intolerance) to ≤2 previous biologic therapies approved for M2S AD in the United States.
The aim of this study is to measure the effectiveness of abrocitinib in a real-world setting in patients with moderate-to-severe atopic dermatitis, with inadequate response or intolerance to ≤2 biologic therapies.
Conditions
- Atopic Dermatitis
- Atopic Dermatitis, Unspecified
- Dermatitis, Atopic
Interventions
- DRUG
-
Abrocitinib
Study Drug for Observational Data Collection.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Eligibility
- Min Age
- 12 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-01-13
- Primary Completion
- 2026-07-01
- Completion
- 2027-02-15
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Study of Abrocitinib Compared With Dupilumab in Adults With Moderate to Severe Atopic Dermatitis on Background Topical Therapy
NCT04345367 ·Status: COMPLETED ·Phase: PHASE3
-
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
NCT07290803 ·Status: RECRUITING
-
Abrocitinib Expanded Access Protocol in Adolescents and Adults With Moderate to Severe Atopic Dermatitis
NCT04564755 ·Status: NO_LONGER_AVAILABLE
-
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
NCT06988605 ·Status: RECRUITING
-
A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis
NCT03568318 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Effectiveness and Safety of Lebrikizumab Treatment in Adults and Adolescents With Moderate-to-Severe Atopic Dermatitis
NCT05990725 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study Evaluating the Mechanism of Action of PF-04965842 Monotherapy for Moderate-to-severe Atopic Dermatitis
NCT03915496 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Abrocitinib in Subjects With Atopic Dermatitis With an Unsatisfactory Response After Treatment With Dupilumab
NCT05602207 ·Status: COMPLETED ·Phase: PHASE4
-
Study of ATI-2138 in Adult Participants With Moderate to Severe Atopic Dermatitis
NCT06585202 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis
NCT07220577 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Learn About Abrocitinib in Adult Patients With Moderate to Severe Atopic Dermatitis
NCT05250115 ·Status: TERMINATED
-
Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy
NCT06283550 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of JNJ-95475939 in the Treatment of Participants With Moderate to Severe Atopic Dermatitis (AD)
NCT06881251 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Effect of OC000459 on Moderate to Severe Atopic Dermatitis
NCT02002208 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Learn About Abrocitinib Tablets in People With Atopic Dermatitis in India
NCT05375929 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase II Study in Adult Patients With Moderate to Severe Atopic Dermatitis
NCT04162899 ·Status: COMPLETED ·Phase: PHASE2
-
A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis
NCT05999799 ·Status: TERMINATED ·Phase: PHASE2
-
Targeted Microbiome Transplant in Atopic Dermatitis
NCT03151148 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis
NCT07230860 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis
NCT02087943 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Extend Efficacy and Safety of SHR-1819 Injection in Adult Patients With Moderate to Severe Atopic Dermatitis
NCT06012812 ·Status: COMPLETED ·Phase: PHASE2
-
This Study Will Evaluate the Safety, Tolerability, and Efficacy of ANB032 in Subjects with Moderate to Severe Atopic Dermatitis (AD).
NCT05935085 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Assess Treat-to-Target and Dosing Flexibility of Oral Upadacitinib Tablets in Adult Participants With Moderate to Severe Atopic Dermatitis
NCT05507580 ·Status: COMPLETED ·Phase: PHASE4
-
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
NCT06947993 ·Status: RECRUITING ·Phase: PHASE2
-
Lebrikizumab in Moderate-to-severe Atopic Dermatitis
NCT06906497 ·Status: RECRUITING ·Phase: PHASE4