Prospective Cohort of People Starting Treatment for Tuberculosis Disease in France (FrenchTB)

Summary

The French Tuberculosis Cohort is a prospective, national, multicenter, low-intervention study including subjects aged 18 years and older with tuberculosis disease for which inpatient treatment is initiated. The goal of this observational study is to follow-up and anti-tuberculosis treatment will be provided according to current French recommendations. Participants will provide sociodemographic, clinical, biological, radiological and bacteriological data at various protocol visits at 2 days, 1 and 2 weeks, 2 months, at the end of treatment, 12 and 24 months. Consenting participants will have samples collected at scheduled visits for the establishment of a biobank. This will include blood, urine, breath and hair samples. The positive mycobacterial strains will constitute a specimen bank.

Conditions

• Tuberculosis

Sponsors & Collaborators

• University of Bordeaux

  collaborator OTHER

• Amiens University Hospital

  collaborator OTHER

• Centre National de la Recherche Scientifique, France

  collaborator OTHER

• Saint Antoine University Hospital

  collaborator OTHER

• University of Lyon

  collaborator OTHER

• Claude Bernard University

  collaborator OTHER

• University Hospital, Bordeaux

  collaborator OTHER

• Saint-Louis Hospital, Paris, France

  collaborator OTHER

• Centre Hospitalier Universitaire, Amiens

  collaborator OTHER

• Hôpital Jean Verdier

  collaborator OTHER

• Institut National de la Santé Et de la Recherche Médicale, France

  collaborator OTHER_GOV

• ANRS, Emerging Infectious Diseases

  lead OTHER_GOV

Principal Investigators

• Nathalie DE CASTRO, MD PHD · Hôpital Saint Louis Paris

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-06-30

Primary Completion

2027-06-30

Completion

2031-06-30