Korean Joint Registry for Alzheimer's Treatment and Diagnostics (JOY-ALZ)
NCT06889818 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 4000
Last updated 2025-03-21
Summary
The purpose of this research is to investigate the long-term effectiveness and safety of new Alzheimer's disease treatments, particularly monoclonal antibody therapies like lecanemab and donanemab, as well as to enhance diagnostic methods for Alzheimer's disease by collecting real-world data from Korean Alzheimer's patients. The goal is to contribute to the precision of Alzheimer's treatment and to evaluate the impact of these new therapies and diagnostic techniques in clinical practice.
Conditions
- Mild Cognitive Impairment
- Dementia
- Subjective Cognitive Decline (SCD)
- Alzheimer Disease
Sponsors & Collaborators
-
Korean Dementia Association
collaborator UNKNOWN -
Inha University Hospital
collaborator OTHER -
Gachon University Gil Medical Center
collaborator OTHER -
Saint Vincent's Hospital, Korea
collaborator OTHER -
Gangnam Severance Hospital
collaborator OTHER -
Konkuk University Hospital
collaborator OTHER -
Kyunghee University Medical Center
collaborator OTHER -
Korea University Medicine
collaborator UNKNOWN -
Busan University Medical Center
collaborator UNKNOWN -
CHA University
collaborator OTHER -
Samsung Medical Center
collaborator OTHER -
Seoul National University Hospital
collaborator OTHER -
Seoul National University Bundang Hospital
collaborator OTHER -
Asan Medical Center
collaborator OTHER -
Soonchunhyang University Hospital
collaborator OTHER -
Ajou University Hospital, Suwon, South Korea
collaborator UNKNOWN -
Yonsei University Yongin Severance Hospital
collaborator UNKNOWN -
Wonkwang University Hospital
collaborator OTHER -
Ewha Womans University Seoul Hospital
collaborator OTHER -
InjeUniversityBusanPaikHospital
collaborator UNKNOWN -
Chonnam National University Hospital
collaborator OTHER -
Jeju National University Hospital
collaborator OTHER -
Chungnam National University Hospital
collaborator OTHER -
Gyungbook national university hospital
collaborator UNKNOWN -
Hanllym University Medical Center
collaborator UNKNOWN -
Heavenly Clinical Research
collaborator OTHER -
KangWon National University Hospital
collaborator OTHER -
Seoul St. Mary's Hospital, The Catholic University
collaborator UNKNOWN -
Ewha Womans University Mokdong Hospital
lead OTHER
Principal Investigators
-
Geon-ha Kim · Ewha Womans University Mokdong Hospital
-
Seong-hye Choi · Inha University Hospital
-
Kee-hyung Park · Gachon University Gil Medical Center
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-02-24
- Primary Completion
- 2034-12-31
- Completion
- 2034-12-31
Countries
- South Korea
Study Locations
More Related Trials
-
Cognitive Changes in Alzheimer's Disease Patients Associated With or Without White Matter Changes After Rivastigmine
NCT01380288 ·Status: COMPLETED ·Phase: NA
-
The Clinical Trial of Low Dose Irradiation for Alzheimer's Disease
NCT05635968 ·Status: COMPLETED ·Phase: PHASE2
-
Lecanemab for Early Onset Familial Alzheimer's Disease
NCT06883019 ·Status: RECRUITING
-
Clinical Research Center for Dementia of South Korea (CREDOS)(or CRCD)
NCT01198093 ·Status: UNKNOWN
-
Cognitive Neurology Unit Clinical Registry
NCT05925621 ·Status: RECRUITING
-
Study to Evaluate the Efficacy and Safety of KDS2010 in Patients With Alzheimer's Disease With Mild Cognitive Impairment and Mild Dementia Due to Alzheimer's Disease
NCT07027072 ·Status: RECRUITING ·Phase: PHASE2
-
The Safety and Scientific Validity of Low-dose Whole Brain Radiotherapy in Alzheimer's Disease.
NCT04203121 ·Status: UNKNOWN ·Phase: NA
-
Olfactory Neuroepithelial Tissue of Alzheimer Disease
NCT02129452 ·Status: COMPLETED
-
Blood Gene Expression Signature in Patients Diagnosed With Probable Alzheimer's Disease Compared to Patients Suffering From Other Types of Dementia
NCT00880347 ·Status: COMPLETED ·Phase: NA
-
Prospective Cohort Study of Patients With Early Alzheimer's Disease Treated With Lecanemab
NCT06741553 ·Status: RECRUITING
-
Characteristics of Treatment Responders to Galantamine
NCT01029132 ·Status: COMPLETED ·Phase: NA
-
Clinical Trial of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia
NCT01023867 ·Status: COMPLETED ·Phase: NA
-
An Observational Study on Lecanemab Treatment for Early Alzheimer's Disease
NCT07153848 ·Status: RECRUITING
-
Effects of LY2062430 in Subjects With Mild-to-Moderate Alzheimer's Disease and in Healthy Volunteers
NCT00329082 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Safety and Potential Therapeutic Effects of CB-AC-02 in Patients With Alzheimer's Disease
NCT02899091 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Evaluating the Efficacy of Artificial Intelligence-based Computer Aided Diagnosis Software That Assists in Determining Whether or Not to Conduct Amyloid PET for the Diagnosis of Alzheimer's Disease by Predicting Amyloid PET Positivity in Mild Cognitive Impairment Patients
NCT05383053 ·Status: COMPLETED
-
Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease
NCT05811442 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease
NCT02097056 ·Status: COMPLETED ·Phase: PHASE4
-
Prospective Monocentric Study of Taste in Patients With Minor or Major Cognitive Disorders Such as Alzheimer's, Through the Analysis of Gustatory Evoked Potentials.
NCT04860414 ·Status: COMPLETED ·Phase: NA
-
Multi-parameter Diagnostic Blood Test for the Diagnosis of Alzheimer's Disease
NCT02409030 ·Status: COMPLETED
-
A Study of LY3372993 in Participants With Alzheimer's Disease (AD) and Healthy Participants
NCT04451408 ·Status: COMPLETED ·Phase: PHASE1
-
Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease
NCT01561430 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study
NCT02488720 ·Status: COMPLETED
-
Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease
NCT06079190 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Effects of 3-Month Melatonin Treatment on Regional Cerebellar Structure and Blood Biomarkers in Alzheimer's Disease Spectrum
NCT06756828 ·Status: NOT_YET_RECRUITING ·Phase: NA